Journal of Pharmacy And Bioallied Sciences
Journal of Pharmacy And Bioallied Sciences Login  | Users Online: 3768  Print this pageEmail this pageSmall font sizeDefault font sizeIncrease font size 
    Home | About us | Editorial board | Search | Ahead of print | Current Issue | Past Issues | Instructions | Online submission

Year : 2009  |  Volume : 1  |  Issue : 1  |  Page : 8-15

High speed counter current chromatography: A support-free LC technique

1 School of Pharmaceutical Sciences, Jaipur National University, Jaipur, India
2 Ranbaxy Research Laboratories, Gurgaon, India

Correspondence Address:
Neha Sethi
School of Pharmaceutical Sciences, Jaipur National University, Jaipur
Login to access the Email id

Source of Support: None, Conflict of Interest: None

DOI: 10.4103/0975-7406.62680

Rights and Permissions

As separation of components is the major requirement of an analytical chemist, there is always a need for a convenient high throughput technique with minimum sample loss, high efficiency, high resolution, and ease of sample recovery, without contamination. This leads to the development of High Speed Counter Current Chromatography (HSCCC), in which the stationary phase is liquid instead of solid, and that provides a lot of advantages over other chromatographic techniques. In addition, advanced centrifugal partition technology is used to hold the liquid stationary phase in the column, while the liquid mobile phase is pushed through it, which provides high yield and purity. This review highlights the major applications of HSCCC that include extraction of medicinal drugs from plants and purification and isolation of active material, plant analysis, separation of rare earth elements, preparative-scale separations of chiral compounds, analysis of inorganic compounds and elements, drug discovery, and drug development. Separation of dipeptides and proteins, flavonoids, alkaloids, DNP amino acids, indole auxins, and so on, proves the versatile and dynamic nature of the technique.

Print this article     Email this article
 Next article
 Previous article
 Table of Contents

 Similar in PUBMED
   Search Pubmed for
   Search in Google Scholar for
 Related articles
 Citation Manager
 Access Statistics
 Reader Comments
 Email Alert *
 Add to My List *
 * Requires registration (Free)

 Article Access Statistics
    PDF Downloaded396    
    Comments [Add]    
    Cited by others 5    

Recommend this journal