| ORIGINAL ARTICLE |
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| Year : 2013 | Volume
: 5
| Issue : 3 | Page : 208-213 |
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Tobacco addiction augments obesity and carcinogenesis: Matter of concern for Indian patients
AK Singh1, A Pandey1, M Tewari1, BP Singh2, HP Pandey3, HS Shukla1
1 Department of Surgical Oncology, Faculty of Medicine, Institute of Medical Sciences, Varanasi, India
2 Division of Statistics, Faculty of Commerce, Banaras Hindu University, Varanasi, India
3 Department of Biochemistry, Faculty of Science, Banaras Hindu University, Varanasi, India
Correspondence Address:
H S Shukla
Department of Surgical Oncology, Faculty of Medicine, Institute of Medical Sciences, Varanasi
India
 Source of Support: Funding support of this work includes Dr. D. S. Kothari Post Doctoral Fellowships from the University Grants Commission [No.F.4/2006 (BSR)/13-581/2012(BSR)]. This study was supported by a research grant from University Grants Commission, availed through Banaras Hindu University DSK-PDF contingency. There is no other financial interest to be declared, Conflict of Interest: None  | Check |
DOI: 10.4103/0975-7406.116819
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Purpose: Life-style and tobacco addiction is the major risk factors for cancer progression in all over the world. Knowledge gaps between tobacco addiction, obesity and cancer in Indian patients brought an interdisciplinary group of investigators together to discuss the present study. Patients and Methods: We calculated the body mass index (BMI) of all the patients (N = 927) who were diagnosed with cancer for its treatment. National Institutes of Health (NIH) criteria were used to categorize the patients. All the patients of this disease could be contacted in person to find out the history of the disease. Results: The frequency of addiction in urban cancer patient was found to be about 53.3% and in a rural area it was only 33.7%. Tobacco addiction was independently associated with younger age of cancer patient (odds ratio [OR] 2.242; 95% Confidence interval (CI) 1.653-3.042), obese (OR 7.433; 95% CI 3.746-14.750), overweight (OR 4.676; 95% CI 3.381-6.468) and advanced stage of cancer (OR 11.950; 95% CI 5.283-27.030). Conclusion: Tobacco consumption appears to be a major contributor to cancer in younger age with elevated BMI in India. Rapid changes in diet and life-style, increase in tobacco consumption appear to be strongly associated with the carcinoma in this middle-income country. |
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