DENTAL SCIENCE - CASE REPORT |
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Year : 2015 | Volume
: 7
| Issue : 6 | Page : 756-758 |
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Stevens-Johnson syndrome induced by a combination of lamotrigine and valproic acid
S Kavitha1, T Anbuchelvan2, V Mahalakshmi1, R Sathya1, TR Sabarinath1, N Gururaj1, S Kalaivani3
1 Department of Oral Pathology and Microbiology, CSI College of Dental Sciences and Research, Madurai, Tamil Nadu, India 2 Department of Pharmacology, Tagore Medical College, Chennai, Tamil Nadu, India 3 Department of Periodontics, CSI College of Dental Sciences and Research, Madurai, Tamil Nadu, India
Correspondence Address:
S Kavitha Department of Oral Pathology and Microbiology, CSI College of Dental Sciences and Research, Madurai, Tamil Nadu India
 Source of Support: None, Conflict of Interest: None  | Check |
DOI: 10.4103/0975-7406.163545
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Lamotrigine and valproic acid are well-tolerated anticonvulsants, but frequently associated with severe cutaneous reactions, such as the Stevens-Johnson syndrome (SJS) and toxic epidermal necrolysis, when used in combination. We report a case of SJS likely induced by the use of a lamotrigine and valproic acid regimen and as a dental surgeon it is important to identify such lesion and report to pharmacovigilance. |
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