Evaluation of preoperative salivary cortisol level in patients undergoing major maxillofacial surgery

Archana Kumari; Praveen Chandra; Sonali Roy; Ritika Agarwal; Aartika Singh; Suprabha Sharan

doi:10.4103/jpbs.JPBS_598_20

Journal of Pharmacy And Bioallied Sciences

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ORIGINAL ARTICLE

Year : 2021 | Volume : 13 | Issue : 5 | Page : 120-123

Evaluation of preoperative salivary cortisol level in patients undergoing major maxillofacial surgery

Archana Kumari¹, Praveen Chandra², Sonali Roy³, Ritika Agarwal⁴, Aartika Singh⁵, Suprabha Sharan⁶
¹ Department of Dentistry, VIMS Pawapuri (Nalanda), Patna, Bihar, India
² Department of Prosthodontics, Buddha Institute of Dental Sciences and Hospital, Patna, Bihar, India
³ Department of Dentistry, Nalanda Medical College and Hospital, Patna, Bihar, India
⁴ Department of Dentistry, Patna Medical College and Hospital, Bihar, India
⁵ Department of Orthodontics and Dentofacial Orthopedics, School of Dental Sciences, Sharda University Greater Noida, Uttar Pradesh, India
⁶ Private Practitioner, Patna, Bihar, India

Correspondence Address:
Sonali Roy
Department of Dentistry, Nalanda Medical College and Hospital, Patna - 800020, Bihar
India

Source of Support: None, Conflict of Interest: None

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DOI: 10.4103/jpbs.JPBS_598_20

Aim: The main purpose of the study was to compare the preoperative salivary cortisol levels 3 days before the major surgery under general anesthesia and to compare it with the patients undergoing extraction under local anesthesia. Materials and Methods: Forty-two patients were undergoing major surgery and 42 age- and sex-matched patients undergoing dental extraction were included and their salivary cortisol levels were analyzed before and after the dental procedure. Results: Results showed that there is a significant increase in the mean salivary cortisol concentration after extraction (23.7 ± 9.2) than before extraction (18.9 ± 23.7) in the study group (P = 0.015) as well as in the control group. The comparison between salivary cortisol in the study group before (18.9 ± 23.7) and after (23.7 ± 9.2) surgery was significantly higher than the control group (15.2 ± 5.5) (P = 0.013 and 0.005), respectively. Conclusion: We have concluded from this study that the salivary cortisol level shows a significant increase on the day of surgery.

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