Cariostatic efficacy of cinnamon water extract on Streptococcus mutans: An In vitro study

Nutan Mala; Sinha Sonal; Amit Kumar; Harsh Vardhan Choudhary; Prafulla Songara; Kumar Ramesh

doi:10.4103/jpbs.JPBS_677_20

Journal of Pharmacy And Bioallied Sciences

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ORIGINAL ARTICLE

Year : 2021 | Volume : 13 | Issue : 5 | Page : 212-216

Cariostatic efficacy of cinnamon water extract on Streptococcus mutans: An In vitro study

Nutan Mala¹, Sinha Sonal², Amit Kumar³, Harsh Vardhan Choudhary⁴, Prafulla Songara⁵, Kumar Ramesh⁶
¹ Department of Conservative Dentistry and Endodontics, Buddha Institute of Dental Science and Hospital, Patna, Bihar, India
² Department of Conservative Dentistry and Endodontics, Dr. B. R. Ambedkar Institute of Dental Sciences and Hospital, Patna, Bihar, India
³ Department of Conservative Dentistry and Endodontics, Mithila Minority Dental College, Darbhanga, Bihar, India
⁴ Dental Surgeon, Public Health Centre, Parwalpur, Nalanda, Bihar, India
⁵ Department of Microbiology, Government Medical College, Ratlam, Madhya Pradesh, India
⁶ Department of Dentistry, Anugrah Narayan Magadh Medical College and Hospital, Gaya, Bihar, India

Correspondence Address:
Prafulla Songara
Department Of Microbiology, Government Medical College, Ratlam, Madhya Pradesh
India

Source of Support: None, Conflict of Interest: None

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DOI: 10.4103/jpbs.JPBS_677_20

Background: Dental caries is a chronic, widespread, and infectious disease affecting the large population. Anticariogenic effects of different herbs and natural products are observed, cinnamon among these, showed the ability to inhibit Streptococcus mutans biofilm. Objectives: The aim of this study was to assess the cinnamon water extract use on nicotine exposed S. mutans biolfilms. Materials and Methods: Microtiter plates having S. mutans culture were treated using varying nicotine concentration range (0–32 mg/ml). These were then either subjected to cinnamon water (2.5 mg/ml) extract or no treatment and analyzed using a spectrophotometer to see planktonic growth, total growth absorbance, and biofilm formation. Results: About 2.5 mg/ml of cinnamon water inhibits the S. mutans biofilm (nicotine-induced) considerably at various nicotine levels (0–32 mg/ml). Conclusion: Cinnamon water extract has a powerful inhibitory effect for S. mutans growth. Nicotine-induced S. mutans growth is markedly reduced by treating with cinnamon water extract.

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