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Year : 2021  |  Volume : 13  |  Issue : 5  |  Page : 52-56

Salivaomics for oral cancer detection: An insight

1 Department of Oral and Maxillofacial Pathology, Malla Reddy Dental College for Women, Hyderabad, Telangana, India
2 Department of Oral and Maxillofacial Pathology, Rajah Muthiah Dental College and Hospital, Chidambaram, Tamil Nadu, India
3 Department of Dental Surgery, MNJ Institute of Oncology and Regional Cancer Centre, Hyderabad, Telangana, India
4 Department of Oral and Maxillofacial Pathology, CKS Theja institute of Dental Sciences, Tirupati, Andhra Pradesh, India
5 Department of Oral Medicine and Radiology, Tirumala Institute of Dental Sciences and Research Centre, Nizamabad, Telangana, India

Correspondence Address:
V Naga Sirisha Chundru
Department of Oral and Maxillofacial Pathology, Malla Reddy Dental College for Women, Hyderabad - 500 055, Telangana
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Source of Support: None, Conflict of Interest: None

DOI: 10.4103/jpbs.JPBS_529_20

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Early detection is very crucial for successful management of oral cancer or any disease as such. Oral squamous cell carcinoma (OSCC) accounts for nearly 90% of malignancy of oral cavity. In the field of cancer research, there is always an ongoing quest for newer methods to lower the morbidity and mortality associated with OSCC. Saliva, a readily available noninvasive biofluid with constant contact with oral cancer lesion, offers an appealing alternative to serum and tissue testing. This review throws light on incorporation of newer technologies for harnessing the saliva to its fullest potential with increased specificity and sensitivity toward identification of cancer-specific molecular signatures for the development of point-of-care applications that could be used at the clinical setting.

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