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ORIGINAL ARTICLE
Year : 2021  |  Volume : 13  |  Issue : 6  |  Page : 1174-1177

Leptin levels in gingival crevicular fluid during orthodontic tooth movement


1 Department of Dental Surgery, Madurai Medical College, Madurai, Tamil Nadu, India
2 Department of Orthodontia, Madha Dental College and Hospital, Chennai, Tamil Nadu, India
3 Department of Oral Medicine and Radiology, CSI Dental College and Hospital, Madurai, Tamil Nadu, India
4 Department of OMFS, Sri Venkateshwara Dental College and Hospital, Chennai, Tamil Nadu, India

Correspondence Address:
Sainath Muthiah Chidambaram
15, Vanamamalai Nagar, 3rd Cross Street, Bye Pass Road, Madurai - 625 016, Tamil Nadu
India
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Source of Support: None, Conflict of Interest: None


DOI: 10.4103/jpbs.jpbs_285_21

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Aim: To evaluate the levels of leptin in gingival crevicular fluid (GCF) during orthodontic tooth movement and to find the role of leptin as a mediator for tooth movement. Materials and Methods: GCF was collected from 25 subjects and the levels of leptin in it were measured. Sample (A) pretreatment, (B) 6 h after applying retractive orthodontic force from right side canine, (C) without retractive force from left side canine, and after 21 days from right canine (D), and left canine (E). Results: GCF Leptin concentration in pretreatment, 6 h control and 21st day control were all similar. GCF leptin concentration at 6 h test tooth site was increased which was statistically significant. GCF leptin concentration in 21st day test tooth was decreased only a little than the control tooth which shows statistically no difference. Conclusion: Leptin is one of the mediators of orthodontic tooth movement.


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