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Thiol antioxidant thioredoxin reductase: A prospective biochemical crossroads between anticancer and antiparasitic treatments of the modern era |
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| Nikhilesh Joardar, Alberto Guevara-Flores, José de J. Martínez-González, Santi P. Sinha Babu |
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| International Journal of Biological Macromolecules. 2020; 165: 249 |
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Spiro-containing derivatives show antiparasitic activity against Trypanosoma brucei through inhibition of the trypanothione reductase enzyme |
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| Lorenzo Turcano, Theo Battista, Esther Torrente De Haro, Antonino Missineo, Cristina Alli, Giacomo Paonessa, Gianni Colotti, Steven Harper, Annarita Fiorillo, Andrea Ilari, Alberto Bresciani, Grace Adira Murilla |
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| PLOS Neglected Tropical Diseases. 2020; 14(5): e0008339 |
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Quinolizidine-Derived Lucanthone and Amitriptyline Analogues Endowed with Potent Antileishmanial Activity |
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| Michele Tonelli, Anna Sparatore, Nicoletta Basilico, Loredana Cavicchini, Silvia Parapini, Bruno Tasso, Erik Laurini, Sabrina Pricl, Vito Boido, Fabio Sparatore |
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| Edézio Ferreira Cunha-Júnior,Valter Viana Andrade-Neto,Marta Lopes Lima,Thais Alves da Costa-Silva,Andres J. Galisteo Junior,Maria A. Abengózar,Coral Barbas,Luis Rivas,Elmo Eduardo Almeida-Amaral,Andre Gustavo Tempone,Eduardo Caio Torres-Santos,Michael P Pollastri |
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Identification of potential trypanothione reductase inhibitors among commercially available
$$\upbeta $$
ß
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| Jorge Rodríguez-Becerra,Lizethly Cáceres-Jensen,José Hernández-Ramos,Lorena Barrientos |
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| Rafael da Rosa,Milene Höehr de Moraes,Lara Almida Zimmermann,Eloir Paulo Schenkel,Mario Steindel,Lílian Sibelle Campos Bernardes |
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Improved proteolytic stability and potent activity against Leishmania infantum trypanothione reductase of a/ß-peptide foldamers conjugated to cell-penetrating peptides |
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| Héctor de Lucio,Ana María Gamo,Marta Ruiz-Santaquiteria,Sonia de Castro,Pedro A. Sánchez-Murcia,Miguel A. Toro,Kilian Jesús Gutiérrez,Federico Gago,Antonio Jiménez-Ruiz,María-José Camarasa,Sonsoles Velázquez |
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