| 1 |
Ruthenium(II)-Catalyzed Direct
Ortho
Functionalization of 1-Arylpyrazoles with Maleimides: A Condition Controlled Installation of Succinimides and Maleimides on Arenes
|
|
|
| Sagar D. Nale, Raju S. Thombal, Yong Rok Lee |
|
| Asian Journal of Organic Chemistry. 2021; 10(9): 2374 |
|
| [Pubmed] [Google Scholar] [DOI] |
|
| 2 |
Iridium-Catalyzed Regio- and Enantioselective Borylation of Unbiased Methylene C(sp
3
)-H Bonds at the Position ß to a Nitrogen Center
|
|
|
| Rongrong Du, Luhua Liu, Senmiao Xu |
|
| Angewandte Chemie. 2021; 133(11): 5907 |
|
| [Pubmed] [Google Scholar] [DOI] |
|
| 3 |
Iridium-Catalyzed Regio- and Enantioselective Borylation of Unbiased Methylene C(sp
3
)-H Bonds at the Position ß to a Nitrogen Center
|
|
|
| Rongrong Du, Luhua Liu, Senmiao Xu |
|
| Angewandte Chemie International Edition. 2021; 60(11): 5843 |
|
| [Pubmed] [Google Scholar] [DOI] |
|
| 4 |
Design and synthesis of ferrocene-tethered pyrazolines and pyrazoles: Photophysical studies, protein-binding behavior with bovine serum albumin, and antiproliferative activity against MDA-MB-231 triple negative breast cancer cells |
|
|
| Koena Ghosh, Nipa Nayek, Subhomoy Das, Nabendu Biswas, Samraj Sinha |
|
| Applied Organometallic Chemistry. 2021; 35(7) |
|
| [Pubmed] [Google Scholar] [DOI] |
|
| 5 |
In silico studies, nitric oxide, and cholinesterases inhibition activities of pyrazole and pyrazoline analogs of diarylpentanoids |
|
|
| Siti Munirah Mohd Faudzi, S. Wei Leong, Faruk A. Auwal, Faridah Abas, Lam K. Wai, Syahida Ahmad, Chau L. Tham, Khozirah Shaari, Nordin H. Lajis, Bohari M. Yamin |
|
| Archiv der Pharmazie. 2021; 354(1): 2000161 |
|
| [Pubmed] [Google Scholar] [DOI] |
|
| 6 |
Urea derivatives of piperazine doped with pyrazole-4-carboxylic acids: Synthesis and antimicrobial evaluation |
|
|
| Harshita Phougat, Vandana Devi, Sanjay Rai, T. Shreedhar Reddy, Karan Singh |
|
| Journal of Heterocyclic Chemistry. 2021; 58(10): 1992 |
|
| [Pubmed] [Google Scholar] [DOI] |
|
| 7 |
Design, synthesis, antibacterial evaluation and molecular docking studies of novel pyrazole/1,2,4-oxadiazole conjugate ester derivatives |
|
|
| Navaneetha Depa, Harikrishna Erothu |
|
| Medicinal Chemistry Research. 2021; 30(5): 1087 |
|
| [Pubmed] [Google Scholar] [DOI] |
|
| 8 |
Design, synthesis, in vitro determination and molecular docking studies of 4-(1-(tert-butyl)-3-phenyl-1H-pyrazol-4-yl) pyridine derivatives with terminal sulfonamide derivatives in LPS-induced RAW264.7 macrophage cells |
|
|
| Karim I. Mersal, Mohammed S. Abdel-Maksoud, Eslam M. H. Ali, Usama M. Ammar, Seyed-Omar Zaraei, Jae-Min Kim, Su-Yeon Kim, Kyung-Tae Lee, Kwan Hyi Lee, Si-Won Kim, Hyun-Mee Park, Mi-Jung Ji, Chang-Hyun Oh |
|
| Medicinal Chemistry Research. 2021; 30(10): 1925 |
|
| [Pubmed] [Google Scholar] [DOI] |
|
| 9 |
Exploration of chalcones and related heterocycle compounds as ligands of adenosine receptors: therapeutics development |
|
|
| Chrisna Matthee, Gisella Terre’Blanche, Lesetja J. Legoabe, Helena D. Janse van Rensburg |
|
| Molecular Diversity. 2021; |
|
| [Pubmed] [Google Scholar] [DOI] |
|
| 10 |
The inhibitory potency of isoxazole-curcumin analogue for the management of breast cancer: A comparative in vitro and molecular modeling investigation |
|
|
| Fiona C. Rodrigues, N. V. Anil Kumar, Gangadhar Hari, K. S. R. Pai, Goutam Thakur |
|
| Chemical Papers. 2021; 75(11): 5995 |
|
| [Pubmed] [Google Scholar] [DOI] |
|
| 11 |
Synthesis and biological evaluation of 3,5-substituted pyrazoles as possible antibacterial agents |
|
|
| Matthew Payne, Amy L. Bottomley, Anthony Och, Anjar P. Asmara, Elizabeth J. Harry, Alison T. Ung |
|
| Bioorganic & Medicinal Chemistry. 2021; 48: 116401 |
|
| [Pubmed] [Google Scholar] [DOI] |
|
| 12 |
Targeting NF-?B mediated cell signaling pathway and inflammatory mediators by 1,2-diazole in A549 cells in vitro |
|
|
| Venugopal Vinod Prabhu, Perumal Elangovan, Sivasithambaram Niranjali Devaraj, Kunnathur Murugesan Sakthivel |
|
| Biotechnology Reports. 2021; 29: e00594 |
|
| [Pubmed] [Google Scholar] [DOI] |
|
| 13 |
An expeditious one pot green synthesis of novel bioactive 1, 4-dihydropyridine derivatives at ambient temperature and molecular modelling |
|
|
| Kailas A. More, Nilesh V. Gandhare, Parvez S. Ali, Naziyanaz B. Pathan, Khalid M. Al-Mousa |
|
| Current Research in Green and Sustainable Chemistry. 2021; 4: 100108 |
|
| [Pubmed] [Google Scholar] [DOI] |
|
| 14 |
Antibacterial and antitumoral properties of 1,2,3-triazolo fused triterpenes and their mechanism of inhibiting the proliferation of HL-60 cells |
|
|
| Rui Wang, Yang Li, Haibo Hu, Leentje Persoons, Dirk Daelemans, Steven De Jonghe, Walter Luyten, Besir Krasniqi, Wim Dehaen |
|
| European Journal of Medicinal Chemistry. 2021; 224: 113727 |
|
| [Pubmed] [Google Scholar] [DOI] |
|
| 15 |
Cu(II) and Ag(I) complexes of the pyrazole-derived diorganoselenide (pzCH2CH2)2Se. Synthesis, solid state structure and solution behavior |
|
|
| Roxana A. Popa, Vito Lippolis, Anca Silvestru |
|
| Inorganica Chimica Acta. 2021; 520: 120272 |
|
| [Pubmed] [Google Scholar] [DOI] |
|
| 16 |
Synthesis of functionalized fluoroalkyl pyrimidines and pyrazoles from fluoroalkyl enones |
|
|
| Elena N. Shaitanova, Olga A. Balabon, Antonina N. Rybakova, Tatyana S. Khlebnicova, Fedor A. Lakhvich, Igor I. Gerus |
|
| Journal of Fluorine Chemistry. 2021; 252: 109905 |
|
| [Pubmed] [Google Scholar] [DOI] |
|
| 17 |
Correlation between corrosion inhibition efficiency in sulfuric acid medium and the molecular structures of two newly eco-friendly pyrazole derivatives on iron oxide surface |
|
|
| N. Mechbal, M.E. Belghiti, N. Benzbiria, Chin-Hung Lai, Y. Kaddouri, Y. Karzazi, R. Touzani, M. Zertoubi |
|
| Journal of Molecular Liquids. 2021; 331: 115656 |
|
| [Pubmed] [Google Scholar] [DOI] |
|
| 18 |
Rational Design, Synthesis and SAR Study of Novel Warfarin Analogous Of 4-Hydroxy Coumarin-Beta-Aryl Propanoic Acid Derivatives as Potent Anti-Inflammatory Agents. |
|
|
| Varsha Pawar, Lokesh A. Shastri, Parashuram Gudimani, Shrinivas Joshi, Vijay M. Kumbar, Vinay Sunagar |
|
| Journal of Molecular Structure. 2021; : 132300 |
|
| [Pubmed] [Google Scholar] [DOI] |
|
| 19 |
Synthesis, structural and pharmacological exploration of 2-(3, 5-dimethyl-1H-pyrazol-1-yl)-acetophenone oximes and their silver complexes |
|
|
| Tulika Sharma, Rakesh Kumar, Subash Chandra Sahoo, Jayant Sindhu, Joginder Singh, Bijender Singh, Surinder Kumar Mehta, Ahmad Umar, Tej Singh Saini, Vinod Kumar, Ramesh Kataria |
|
| Polyhedron. 2021; 195: 114972 |
|
| [Pubmed] [Google Scholar] [DOI] |
|
| 20 |
Investigating ESIPT and donor-acceptor substituent effects on the photophysical and electrochemical properties of fluorescent 3,5-diaryl-substituted 1-phenyl-2-pyrazolines |
|
|
| Gabriel C. Santos, Inaiá O. Rocha, Felipe S. Stefanello, João P. P. Copetti, Isadora Tisoco, Marcos A. P. Martins, Nilo Zanatta, Clarissa P. Frizzo, Bernardo A. Iglesias, Helio G. Bonacorso |
|
| Spectrochimica Acta Part A: Molecular and Biomolecular Spectroscopy. 2021; : 120768 |
|
| [Pubmed] [Google Scholar] [DOI] |
|
| 21 |
Pd-catalyzed post-Ugi intramolecular cyclization to the synthesis of isoquinolone-pyrazole hybrid pharmacophores & discover their antimicrobial and DFT studies |
|
|
| Keyur M. Pandya, Satyanarayana Battula, Parth J. Naik |
|
| Tetrahedron Letters. 2021; 81: 153353 |
|
| [Pubmed] [Google Scholar] [DOI] |
|
| 22 |
New 1,2,3-Triazole-Appended Bis-pyrazoles: Synthesis, Bioevaluation, and Molecular Docking |
|
|
| Ashruba B. Danne, Mukund V. Deshpande, Jaiprakash N. Sangshetti, Vijay M. Khedkar, Bapurao B. Shingate |
|
| ACS Omega. 2021; 6(38): 24879 |
|
| [Pubmed] [Google Scholar] [DOI] |
|
| 23 |
Conventional and Microwave-Assisted Synthesis, Antitubercular Activity, and Molecular Docking Studies of Pyrazole and Oxadiazole Hybrids |
|
|
| Nisheeth C. Desai, Kandarp Bhatt, Jahnvi Monapara, Unnat Pandit, Vijay M. Khedkar |
|
| ACS Omega. 2021; 6(42): 28270 |
|
| [Pubmed] [Google Scholar] [DOI] |
|
| 24 |
Xanthohumol Pyrazole Derivative Improves Diet-Induced Obesity and Induces Energy Expenditure in High-Fat Diet-Fed Mice |
|
|
| Ines L. Paraiso, Luce M. Mattio, Armando Alcázar Magaña, Jaewoo Choi, Layhna S. Plagmann, Margaret A. Redick, Cristobal L. Miranda, Claudia S. Maier, Sabrina Dallavalle, Chrissa Kioussi, Paul R. Blakemore, Jan F. Stevens |
|
| ACS Pharmacology & Translational Science. 2021; |
|
| [Pubmed] [Google Scholar] [DOI] |
|
| 25 |
Catalytic enantioselective synthesis of chiral 4-hydroxy 4'-substituted pyrazolones by the vinylogous aldol reaction of pyrazole-4,5-diones with 3-alkylidene-2-oxindoles |
|
|
| Krishna Kumar, Bhuvnesh Singh, Soumyadip Hore, Ravi P Singh |
|
| New Journal of Chemistry. 2021; 45(31): 13747 |
|
| [Pubmed] [Google Scholar] [DOI] |
|
| 26 |
Monoallylation and benzylation of dicarbonyl compounds with alcohols catalysed by a cationic cobalt(iii) compound |
|
|
| Mohan Chandra Sau, Smita Mandal, Manish Bhattacharjee |
|
| RSC Advances. 2021; 11(16): 9235 |
|
| [Pubmed] [Google Scholar] [DOI] |
|
| 27 |
Design and synthesis of novel phthalocyanines as potential antioxidant and antitumor agents starting with new synthesized phthalonitrile derivatives |
|
|
| Afnan M. El-badrawy, Ahmed A. Fadda, Ehab Abdel-Latif, Yasser A. Selim |
|
| RSC Advances. 2021; 11(54): 34300 |
|
| [Pubmed] [Google Scholar] [DOI] |
|
| 28 |
Synthesis, antimicrobial studies, and molecular docking of some new dihydro-1,3,4-thiadiazole and pyrazole derivatives derived from dithiocarbazates |
|
|
| Amr Hassan Moustafa, Doaa H. Ahmed, Mohamed T. M. El-Wassimy, Mamdouh F. A. Mohamed |
|
| Synthetic Communications. 2021; 51(4): 570 |
|
| [Pubmed] [Google Scholar] [DOI] |
|
| 29 |
A combinatorial approach to screen structurally diverse acetylcholinesterase inhibitory plant secondary metabolites targeting Alzheimer’s disease |
|
|
| Gourav Choudhir, Satyawati Sharma, P. Hariprasad |
|
| Journal of Biomolecular Structure and Dynamics. 2021; : 1 |
|
| [Pubmed] [Google Scholar] [DOI] |
|
| 30 |
Low-temperature crystal structure of 4-chloro-1H-pyrazole |
|
|
| Kelly Rue, Raphael G. Raptis |
|
| Acta Crystallographica Section E Crystallographic Communications. 2021; 77(9): 955 |
|
| [Pubmed] [Google Scholar] [DOI] |
|
| 31 |
Synthesis of 4,4'-(arylmethylene)bis(3-methyl-1-phenyl-1H-pyrazol-5-ols) and evaluation of their antioxidant and anticancer activities |
|
|
| José Eduardo Cadena-Cruz, Luis M. Guamán-Ortiz, Juan Carlos Romero-Benavides, Natalia Bailon-Moscoso, Kevin E. Murillo-Sotomayor, Nadia V. Ortiz-Guamán, Jorge Heredia-Moya |
|
| BMC Chemistry. 2021; 15(1) |
|
| [Pubmed] [Google Scholar] [DOI] |
|
| 32 |
Appraisal of the Role of In silico Methods in Pyrazole Based Drug Design |
|
|
| Smriti Sharma, Vinayak Bhatia |
|
| Mini-Reviews in Medicinal Chemistry. 2021; 21(2): 204 |
|
| [Pubmed] [Google Scholar] [DOI] |
|
| 33 |
INVESTIGATIONS ON ANTIMICROBIAL AND ANTITUBERCULAR ACTIVITY OF SOME 4,5-DIHYDRO-1H-PYRAZOLE AND CHALCONE DERIVATIVES |
|
|
| Begüm EVRANOS AKSÖZ, Fatma Kaynak KAYNAK ONURDAG, Erkan AKSÖZ, Selda ÖZGEN |
|
| Ankara Universitesi Eczacilik Fakultesi Dergisi. 2021; : 6 |
|
| [Pubmed] [Google Scholar] [DOI] |
|
| 34 |
Assessment of Computational Tools for Predicting Supramolecular Synthons |
|
|
| Bhupinder Sandhu, Ann McLean, Abhijeet S. Sinha, John Desper, Christer B. Aaker?y |
|
| Chemistry. 2021; 3(2): 612 |
|
| [Pubmed] [Google Scholar] [DOI] |
|
| 35 |
Pyrazoles and Pyrazolines as Anti-Inflammatory Agents |
|
|
| Martha Mantzanidou, Eleni Pontiki, Dimitra Hadjipavlou-Litina |
|
| Molecules. 2021; 26(11): 3439 |
|
| [Pubmed] [Google Scholar] [DOI] |
|
| 36 |
Synthesis and Evaluation of Biological Activities of Bis(spiropyrazolone)cyclopropanes: A Potential Application against Leishmaniasis |
|
|
| Olalla Barreiro-Costa, Gabriela Morales-Noboa, Patricio Rojas-Silva, Eliana Lara-Barba, Javier Santamaría-Aguirre, Natalia Bailón-Moscoso, Juan Carlos Romero-Benavides, Ana Herrera, Cristina Cueva, Lenin Ron-Garrido, Ana Poveda, Jorge Heredia-Moya |
|
| Molecules. 2021; 26(16): 4960 |
|
| [Pubmed] [Google Scholar] [DOI] |
|
| 37 |
Synthesis of 3,5-Bis(trifluoromethyl)phenyl-Substituted Pyrazole Derivatives as Potent Growth Inhibitors of Drug-Resistant Bacteria |
|
|
| Ibrahim S. Alkhaibari, Hansa Raj KC, Subrata Roy, Mohd. K. Abu-gazleh, David F. Gilmore, Mohammad A. Alam |
|
| Molecules. 2021; 26(16): 5083 |
|
| [Pubmed] [Google Scholar] [DOI] |
|
| 38 |
Synthesis of New 1-Aryl-2-(3,5-dimethylpyrazol-1-yl)ethanone Oxime Ether Derivatives and Investigation of Their Cytotoxic Effects |
|
|
| Mehmet Abdullah Alagöz, Arzu Karakurt, Ceylan Hepokur, Emine Salva, Tijen Önkol, Mohammed M. Ghoneim, Mohamed A. Abdelgawad, Ahmed Khames, Hoon Kim, Bijo Mathew |
|
| Processes. 2021; 9(11): 2019 |
|
| [Pubmed] [Google Scholar] [DOI] |
|
| 39 |
Synthesis of Pyrazolo[4,3-c]quinolines and the C-C Bond Cleavage during Reductive Cyclization |
|
|
| Chandi C. Malakar, Virender Singh, Nisha Devi, Antriksh Gupta, Raghuram Gujjarappa |
|
| HETEROCYCLES. 2021; 102(4): 705 |
|
| [Pubmed] [Google Scholar] [DOI] |
|
| 40 |
Synthesis, Antimicrobial Activity and Molecular Docking of Pyrazole Bearing the Benzodiazepine Moiety |
|
|
| Nisheeth. C. Desai, Surbhi B. Joshi, Vijay M. Khedkar |
|
| Analytical Chemistry Letters. 2020; 10(3): 307 |
|
| [Pubmed] [Google Scholar] [DOI] |
|
| 41 |
Microwave Assisted Reactions of Azaheterocycles Formedicinal Chemistry Applications |
|
|
| Dorina Amariucai-Mantu, Violeta Mangalagiu, Ramona Danac, Ionel I. Mangalagiu |
|
| Molecules. 2020; 25(3): 716 |
|
| [Pubmed] [Google Scholar] [DOI] |
|
| 42 |
NSC 18725, a Pyrazole Derivative Inhibits Growth of Intracellular Mycobacterium tuberculosis by Induction of Autophagy |
|
|
| Garima Arora, Gagandeep, Assirbad Behura, Tannu Priya Gosain, Ravi P. Shaliwal, Saqib Kidwai, Padam Singh, Shamseer Kulangara Kandi, Rohan Dhiman, Diwan S. Rawat, Ramandeep Singh |
|
| Frontiers in Microbiology. 2020; 10 |
|
| [Pubmed] [Google Scholar] [DOI] |
|
| 43 |
Synthetic Methods and Antimicrobial Perspective of Pyrazole Derivatives: An Insight |
|
|
| Harish Kumar, Kushal Kumar Bansal, Anju Goyal |
|
| Anti-Infective Agents. 2020; 18(3): 207 |
|
| [Pubmed] [Google Scholar] [DOI] |
|
| 44 |
Nanocrystalline ZnO: A Competent and Reusable Catalyst for the Preparation of Pharmacology Relevant Heterocycles in the Aqueous Medium |
|
|
| Moumita Saha, Asish R. Das |
|
| Current Green Chemistry. 2020; 7(1): 53 |
|
| [Pubmed] [Google Scholar] [DOI] |
|
| 45 |
Synthesis, Characterization, in vitro Antimicrobial Evaluation and in silico
Molecular Docking and ADME Prediction of 4-Chlorophenyl
Furfuran Derivatives bearing Pyrazole Moieties |
|
|
| Manju Mathew, Raja Chinnamanayakar, Ezhilarasi Muthuvel Ramanathan |
|
| Asian Journal of Chemistry. 2020; 32(6): 1482 |
|
| [Pubmed] [Google Scholar] [DOI] |
|
| 46 |
Crystal structure of ethyl 3-(trifluoromethyl)-1H-pyrazole-4-carboxylate, C7H7F3N2O2 |
|
|
| Željko. K. Jacimovic, Sladjana B. Novakovic, Goran A. Bogdanovic, Milica Kosovic, Eugen Libowitzky, Gerald Giester |
|
| Zeitschrift für Kristallographie - New Crystal Structures. 2020; 235(5): 1189 |
|
| [Pubmed] [Google Scholar] [DOI] |
|
| 47 |
Computational Analysis of Dipyrone Metabolite 4-Aminoantipyrine As A Cannabinoid Receptor 1 Agonist |
|
|
| Silvana Russo, Walter Filgueira de Azevedo |
|
| Current Medicinal Chemistry. 2020; 27(28): 4741 |
|
| [Pubmed] [Google Scholar] [DOI] |
|
| 48 |
Highly Efficient Synthesis of New 3,5-Substituted (Isoxazolines) and 2,3,5-Trisubstituted (Pyrazolines) Mediated by Chloramin-T and Their Evaluation of Antioxidant and Antibacterial Activities |
|
|
| Ebraheem Abdu Musad, Abdullah Mohammed Al Dawsari, Zaki Eldin Ali Abdalla, Kakul Husain, Razaz Saeed Saeed Al Sharabi, K. M. Lokanatha Rai |
|
| Russian Journal of Bioorganic Chemistry. 2020; 46(5): 814 |
|
| [Pubmed] [Google Scholar] [DOI] |
|
| 49 |
Pyrazole ligands and their monometallic and bimetallic complexes: synthesis, characterization, and application as novel corrosion inhibitors |
|
|
| Asad Masoumi, Moayad Hossaini Sadr, Behzad Soltani |
|
| Journal of Adhesion Science and Technology. 2020; 34(23): 2569 |
|
| [Pubmed] [Google Scholar] [DOI] |
|
| 50 |
Crystal structure determination of N- and O-alkylated tautomers of 1-(2-pyridinyl)-5-hydroxypyrazole |
|
|
| Venkata S. Sadu, Yoon Mi Choi, Koteswara R. Kamma, Chong-Hyeak Kim, Yun Soo Bae, Kee-In Lee |
|
| Journal of Molecular Structure. 2020; 1215: 128272 |
|
| [Pubmed] [Google Scholar] [DOI] |
|
| 51 |
Nucleophilic Aromatic Substitution of Unactivated Fluoroarenes Enabled by Organic Photoredox Catalysis |
|
|
| Vincent A. Pistritto, Megan E. Schutzbach-Horton, David A. Nicewicz |
|
| Journal of the American Chemical Society. 2020; 142(40): 17187 |
|
| [Pubmed] [Google Scholar] [DOI] |
|
| 52 |
Kinetics modelling of acid hydrolysis of cassava (Manihot esculanta Cranz) peel and its hydrolysate chemical characterisation |
|
|
| E.O. Ajala, M.A. Ajala, I.A. Tijani, A.A. Adebisi, I. Suru |
|
| Journal of King Saud University - Science. 2020; 32(4): 2284 |
|
| [Pubmed] [Google Scholar] [DOI] |
|
| 53 |
Computer-aided discovery of bis-indole derivatives as multi-target drugs against cancer and bacterial infections: DFT, docking, virtual screening, and molecular dynamics studies |
|
|
| Parth Sarthi Sen Gupta, Haamid Rasool Bhat, Satyaranjan Biswal, Malay Kumar Rana |
|
| Journal of Molecular Liquids. 2020; 320: 114375 |
|
| [Pubmed] [Google Scholar] [DOI] |
|
| 54 |
p-TSA.H2O mediated one-pot, multi-component synthesis of isatin derived imidazoles as dual-purpose drugs against inflammation and cancer |
|
|
| M. Rajesh Kumar, V. Violet Dhayabaran, N. Sudhapriya, A. Manikandan, Daniel A. Gideon, S. Annapoorani |
|
| Bioorganic Chemistry. 2020; 102: 104046 |
|
| [Pubmed] [Google Scholar] [DOI] |
|
| 55 |
2,4-Diketo esters: Crucial intermediates for drug discovery |
|
|
| Nenad Joksimovic, Nenad Jankovic, Goran Davidovic, Zorica Bugarcic |
|
| Bioorganic Chemistry. 2020; 105: 104343 |
|
| [Pubmed] [Google Scholar] [DOI] |
|
| 56 |
Recent advancement in the discovery and development of anti-epileptic biomolecules: An insight into structure activity relationship and Docking |
|
|
| Mukund Jha, Ozair Alam, Mohd. Javed Naim, Vrinda Sharma, Parth Bhatia, Aadil Ahmad Sheikh, Farah Nawaz, Perwaiz Alam, Ajay Manaithiya, Vivek Kumar, Shagufi Nazar, Nadeem Siddiqui |
|
| European Journal of Pharmaceutical Sciences. 2020; 153: 105494 |
|
| [Pubmed] [Google Scholar] [DOI] |
|
| 57 |
Copper-Catalyzed Regio- and Stereoselective 1,6-Conjugate Addition of Aza-Heterocycles to 1-Sulfonyl-1,3-dienes |
|
|
| Subin Park, Hanseul Lee, Yunmi Lee |
|
| Advanced Synthesis & Catalysis. 2020; 362(3): 572 |
|
| [Pubmed] [Google Scholar] [DOI] |
|
| 58 |
Transition-Metal-Free C-S Bond Forming Strategy towards Synthesis of Highly Diverse Pyrazole Tethered Benzothiazoles: Investigation of their Photophysical Properties |
|
|
| Shubham Sharma, Chandi C. Malakar, Virender Singh |
|
| Asian Journal of Organic Chemistry. 2020; 9(11): 1857 |
|
| [Pubmed] [Google Scholar] [DOI] |
|
| 59 |
Synthesis of pyrazolopyrimidines in mild conditions by gold nanoparticles supported on magnetic ionic gelation in aqueous solution |
|
|
| Lanlan Yu, Shilong Xing, Kai Zheng, Seyed Mohsen Sadeghzadeh |
|
| Applied Organometallic Chemistry. 2020; 34(7) |
|
| [Pubmed] [Google Scholar] [DOI] |
|
| 60 |
Regioselective Thermal [3+2]-Dipolar Cycloadditions of a-Diazoacetates with
a
-Sulfenyl/Sulfinyl/Sulfonyl-
ß
-Chloroacrylamide Derivatives to Form Densely Functionalised Pyrazoles
|
|
|
| Aaran J. Flynn, Alan Ford, U. B. Rao Khandavilli, Simon E. Lawrence, Anita R. Maguire |
|
| European Journal of Organic Chemistry. 2019; 2019(31-32): 5368 |
|
| [Pubmed] [Google Scholar] [DOI] |
|
| 61 |
Ligand-Dependent Site-Selective Suzuki Cross-Coupling of 4-Bromopyrazol-5-yl Triflates |
|
|
| Ryo Sakakibara, Kennosuke Itoh, Hideaki Fujii |
|
| The Journal of Organic Chemistry. 2019; 84(18): 11474 |
|
| [Pubmed] [Google Scholar] [DOI] |
|
| 62 |
Copper-Catalyzed Aminoboration from Hydrazones To Generate Borylated Pyrazoles |
|
|
| Kim N. Tu, Scott Kim, Suzanne A. Blum |
|
| Organic Letters. 2019; 21(5): 1283 |
|
| [Pubmed] [Google Scholar] [DOI] |
|
| 63 |
DPD-Inspired Discovery of Novel LsrK Kinase Inhibitors: An Opportunity To Fight Antimicrobial Resistance |
|
|
| Silvia Stotani, Viviana Gatta, Prasanthi Medarametla, Mohan Padmanaban, Anna Karawajczyk, Fabrizio Giordanetto, Päivi Tammela, Tuomo Laitinen, Antti Poso, Dimitros Tzalis, Simona Collina |
|
| Journal of Medicinal Chemistry. 2019; 62(5): 2720 |
|
| [Pubmed] [Google Scholar] [DOI] |
|
| 64 |
Selective, Ambient-Temperature C-4 Deuteration of Pyrazole Derivatives by D2O |
|
|
| Basil M. Ahmed, Gellert Mezei |
|
| The Journal of Organic Chemistry. 2018; 83(3): 1649 |
|
| [Pubmed] [Google Scholar] [DOI] |
|
| 65 |
Discovery of Novel Pyrazole-Based Selective Aldosterone Synthase (CYP11B2) Inhibitors: A New Template to Coordinate the Heme-Iron Motif of CYP11B2 |
|
|
| Ryo Sakakibara, Wataru Sasaki, Yuichi Onda, Minami Yamaguchi, Hideki Ushirogochi, Yuki Hiraga, Kanako Sato, Masashi Nishio, Yasuhiro Egi, Kei Takedomi, Hidetoshi Shimizu, Tomoko Ohbora, Fumihiko Akahoshi |
|
| Journal of Medicinal Chemistry. 2018; 61(13): 5594 |
|
| [Pubmed] [Google Scholar] [DOI] |
|
| 66 |
Recent progress on anti-cancer of amide appended heterocyclic and its possible therapeutic applications. A review drug progress for cancer therapeutics. |
|
|
| YASSER HUSSEIN EISSA MOHAMMED, SHAUKATH ARA KHANUM |
|
| International Journal of pharma and Bio Sciences. 2018; 9(2) |
|
| [Pubmed] [Google Scholar] [DOI] |
|
| 67 |
Crystal structure of (E)-5-((4-chlorophenyl)diazenyl)-2-(5-(4-fluorophenyl)-3-(thiophen-2-yl)-4,5-dihydro-1H-pyrazol-1-yl)-4-methylthiazole, C23H17ClFN5S2 |
|
|
| Gamal A. El-Hiti, Bakr F. Abdel-Wahab, Mohammed Baashen, Amany S. Hegazy, Benson M. Kariuki |
|
| Zeitschrift für Kristallographie - New Crystal Structures. 2017; 232(1): 157 |
|
| [Pubmed] [Google Scholar] [DOI] |
|
| 68 |
Chalcone: A valuable scaffold upgrading by green methods |
|
|
| Gonçalo P. Rosa,Ana M. L. Seca,Maria do Carmo Barreto,Diana Cláudia Gouveia Alves Pinto |
|
| ACS Sustainable Chemistry & Engineering. 2017; |
|
| [Pubmed] [Google Scholar] [DOI] |
|
| 69 |
Synthesis, Antimicrobial and Antioxidant Activity of Pyrazole Based Sulfonamide Derivatives |
|
|
| Jagdish R. Badgujar,Dhananjay H. More,Jyotsna S. Meshram |
|
| Indian Journal of Microbiology. 2017; |
|
| [Pubmed] [Google Scholar] [DOI] |
|
| 70 |
Facile one-pot multicomponent synthesis of 1H-pyrazolo[3,4-b]quinolines using L-proline as a catalyst |
|
|
| Hemant Hegde,Nitinkumar S. Shetty |
|
| Chemistry of Heterocyclic Compounds. 2017; |
|
| [Pubmed] [Google Scholar] [DOI] |
|
| 71 |
Synthesis of Functionalized Pyrazoles via
1,3-Dipolar Cycloaddition of a
-Diazo-ß
-ketophosphonates, Sufones and Esters with Electron-Deficient Alkenes |
|
|
| T. V. Baiju,Irishi N. N. Namboothiri |
|
| The Chemical Record. 2017; |
|
| [Pubmed] [Google Scholar] [DOI] |
|
| 72 |
Analgesic, anti-inflammatory, and antimicrobial activities of novel isoxazole/pyrimidine/pyrazole substituted benzimidazole analogs |
|
|
| Krishna Veni Chikkula,Raja Sundararajan |
|
| Medicinal Chemistry Research. 2017; |
|
| [Pubmed] [Google Scholar] [DOI] |
|
| 73 |
Anticancer activity profiling of parthenolide analogs generated via P450-mediated chemoenzymatic synthesis |
|
|
| Hanan Alwaseem,Benjamin J. Frisch,Rudi Fasan |
|
| Bioorganic & Medicinal Chemistry. 2017; |
|
| [Pubmed] [Google Scholar] [DOI] |
|
| 74 |
Experimental and theoretical studies of a pyrazole-thiazolidin-2,4-di-one hybrid |
|
|
| Md. Mushtaque,Fernando Avecilla,Ashanul Haque,Ahmad Perwez,Md. Shahzad Khan,M. Moshahid Alam Rizvi |
|
| Journal of Molecular Structure. 2017; 1141: 417 |
|
| [Pubmed] [Google Scholar] [DOI] |
|
| 75 |
Copper-catalyzed methylation of 1,3-diketones with tert -butyl peroxybenzoate |
|
|
| Zhi-Hao Zhou,Cheng-Kun Li,Shao-Fang Zhou,Adedamola Shoberu,Jian-Ping Zou |
|
| Tetrahedron. 2017; 73(19): 2740 |
|
| [Pubmed] [Google Scholar] [DOI] |
|
| 76 |
Convergent synthesis and cytotoxicity of novel trifluoromethyl-substituted (1H-pyrazol-1-yl)(quinolin-4-yl) methanones |
|
|
| Helio G. Bonacorso,Pablo A. Nogara,Fernanda D’A. Silva,Wilian C. Rosa,Carson W. Wiethan,Nilo Zanatta,Marcos A.P. Martins,João B.T. Rocha |
|
| Journal of Fluorine Chemistry. 2016; 190: 31 |
|
| [Pubmed] [Google Scholar] [DOI] |
|
| 77 |
Brønsted-acidic ionic liquid: green protocol for synthesis of novel tetrasubstituted imidazole derivatives under microwave irradiation via multicomponent strategy |
|
|
| Gopinath D. Shirole,Vijay A. Kadnor,Adinath S. Tambe,Sharad N. Shelke |
|
| Research on Chemical Intermediates. 2016; |
|
| [Pubmed] [Google Scholar] [DOI] |
|
| 78 |
Synthesis, carbonic anhydrase I and II inhibition studies of the 1,3,5-trisubstituted-pyrazolines |
|
|
| Halise Inci Gul,Ebru Mete,Parham Taslimi,Ilhami Gulcin,Claudiu T. Supuran |
|
| Journal of Enzyme Inhibition and Medicinal Chemistry. 2016; : 1 |
|
| [Pubmed] [Google Scholar] [DOI] |
|
