Figure 4 :Upper part: the concentration (φ) profile of a BA inside a multi-lamellar vesicle at different times. r is the multi-lamellar vesicle radius. At t = 0 all the BA molecules are in the external aqueous medium (A). At intermediate times (B) one observes a nonlinear concentration gradient throughout the membrane which becomes linear in the late stages (steady-state C). At t = ?#8225; the BA concentrations in the external and internal aqueous medium become identical (D). Lower part: the corresponding variation of the specific heat (Cp) with temperature (T) at different times. Tm0 is the melting temperature of the unperturbed multi-lamellar vesicle. Adapted from Raudino et al.