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  Indian J Med Microbiol
 

Figure 3: Effect of XAE (30-300 mg kg- 1), XA (10-100 mg kg- 1), morphine (1-10 mg kg- 1) and diclofenac (1-10 mg kg- 1) on the time course curves (a, c, e, g) and the total nociceptive score (calc. as AUCs) (b, d, f, h) of acetic acid-induced writhing in mice. Nociceptive scores are shown in 5 min time blocks up to 30 min for the time course curves. Data are presented as mean ± SEM (n = 7-8). The lower and upper margins of the boxes (b, d, f, h) represent the 25th and 75th percentiles, with the extended arms representing the 10th and 90th percentiles, respectively. The median is shown as the horizontal line within the box.*P < 0.05, **P < 0.01, ***P < 0.001 compared to control group (ctrl) (Two-way repeated measures ANOVA followed by Bonferroni's post hoc). †P < 0.05, ††P < 0.01, †††P < 0.001 compared to control group (ctrl) (one-way ANOVA followed by Newman-Keuls post hoc)

Figure 3: Effect of XAE (30-300 mg kg<b>-</b> 1), XA (10-100 mg kg<b>-</b> 1), morphine (1-10 mg kg<b>-</b> 1) and diclofenac (1-10 mg kg<b>-</b> 1) on the time course curves (a, c, e, g) and the total nociceptive score (calc. as AUCs) (b, d, f, h) of acetic acid-induced writhing in mice. Nociceptive scores are shown in 5 min time blocks up to 30 min for the time course curves. Data are presented as mean ± SEM (<i>n</i> = 7-8). The lower and upper margins of the boxes (b, d, f, h) represent the 25th and 75th percentiles, with the extended arms representing the 10th and 90th percentiles, respectively. The median is shown as the horizontal line within the box.*<i>P</i> < 0.05, **<i>P</i> < 0.01, ***<i>P</i> < 0.001 compared to control group (ctrl) (Two-way repeated measures ANOVA followed by Bonferroni's <i>post hoc</i>). †<i>P</i> < 0.05, ††<i>P</i> < 0.01, †††<i>P</i> < 0.001 compared to control group (ctrl) (one-way ANOVA followed by Newman-Keuls <i>post hoc</i>)